Influenza

Description of Virus:

  • Influenza is an RNA virus that infects birds and mammals, including humans.
  • Influenza comes in three strains: influenzavirus A,B, and C.
  • Typically spherical in shape and 80-120 nanometres in diameter.
  • Virus is enveloped containing two main types of glycoproteins wrapped around a central core.
  • RNA is within central core and is usually double-stranded.
  • Influenza A and B most severe and common while C is usually not as harmful and shows little to no symptoms.
  • Influenza A is transmitted mostly through wild aquatic birds.
  • Most virulent pathogen among humans.
  • Examples include Spanish flu, Swine flu, Bird flu, and Asian flu.
  • Influenza B is not as dangerous and infects mostly humans, seals, and ferrets.
  • Mutates slower than Influenza A which increases immunity.
external image influenzafigure1.jpg

Viral Specificity:

  • Influenza infects the nose, throat, and bronchial tubes.
  • Parts become enflamed,sore, and irritable.
  • Influenza only infects birds, mammals, and humans.
    File:H1N1 versus H5N1 pathology.png
    File:H1N1 versus H5N1 pathology.png
    - Areas of the body affected by Influenza.

Symptoms and progression of the disease:

  • Visible symptoms occur one to two days after infection.
  • Common symptoms include: the chills, fever, sore throat, muscle pains, severe headaches, coughing, weakness and fatique.
  • Symptoms usually reach their peak severity around three to four days.

Common Methods of Transmission:

  • Many modes of transmission.
  • Transmitted throught the air by coughs or sneezes.
  • Bird droppings, nasal secretions or contact with contaminated surfaces.
  • Spreads in seasonal epidemics.
  • Has led to many epidemics and pandemics such as the Spanish flu.
  • The time at which a person becomes infectious is one day before first symptoms.
  • People become most infective between the second and third days.
  • As a person's fever increases, so does the likelihood of infecting others.

Treatment and Prevention:

  • Immunizations are given yearly in developed countries.
  • Influenza is highly adaptable and constantly evolving and replacing older strains.
  • Immunizations do not provide permanent immunity.
  • Most common type of vaccine is a trivalent vaccine that contains purified and inactivated antigens.
  • Immunization must occur within one week to four months prior to exposure.
  • Cases are most serious in the elderly, young children and those with weak immune systems.
  • Previous exposure does not guarantee immunity.
  • Common ways to combat virus include: bed rest, drinking fluids, tylenol or ibuprofen, and antiviral antibiotics.
  • Virus can be inactivated through sunlight, disinfectants, and detergents.
  • Frequent handwashing reduces the risk of infection.

Miscellaneous:

  • Results in 250,00 - 500,000 deaths yearly.
  • On average, 41,400 people died yearly in the United States between 1979-2001.
  • Distantly related to the human parainfluenza viruses
  • 50 to 100 million people, or 3% of the world's population at the time, were killed as a result of Spanish flu with another 500 million, or 23% of the world population infected.
  • More people died because of Spanish flu than World War 1.
  • Although somewhat of a cliche, washing your hands is an EXTREMELY effective way of preventing the disease.

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